Cockayne Pelizaeus Merzbacher Disease (CPMD) is a rare genetic disorder that affects the central nervous system. CPMD is characterized by a myelin deficiency, resulting in severe neurological impairments. While there are no direct synonyms for CPMD, it is often classified under the broader category of leukodystrophies or hypomyelinating leukodystrophies. These terms describe a group of genetic conditions that involve abnormal myelin formation or maintenance. Other related terms may include Pelizaeus-Merzbacher-like disease (PMLD) or Pelizaeus-Merzbacher disease-like (PMD-like) conditions, which share similar clinical features to CPMD but have different genetic causes. While these terms are not exact synonyms, they may be used interchangeably in medical literature to refer to similar neurological disorders.