Most weighted, a phrase used to describe something that has the greatest influence or importance, can have several antonyms. Some of the antonyms for most weighted include least significant, inessential, unimportant, trivial, and inconsequential. These words denote the opposite of something that is most weighted and suggest that the subject in question is of little consequence or has little impact. By using these antonyms, one can convey a different meaning or shift the tone of the sentence to emphasize non-importance. Overall, antonyms for most weighted can be useful when trying to communicate a specific perspective or emphasize a different interpretation of a situation.