There are several antonyms for the word "qualmiest" which means feeling uneasy or queasy. Some possible antonyms include "comfortable," "relaxed," "calm," "at ease," and "settled." These words connote a sense of security, peace, and contentment, which is completely opposite to the feeling of being nauseous or uneasy. One can also use words such as "confident," "assured," "pleased," "happy," or "satisfied" to express the opposite meaning. Using antonyms allows one to describe a range of emotions, avoiding monotony and repetition. Overall, using antonyms adds depth and complexity to any writing or conversation.